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 技術查詢及媒合洽談 



技術名稱:
精子分選器與精子分選方法
SPERM SORTER AND SPERM SORTING METHOD
單位/學校:
國立清華大學
NATIONAL TSING HUA UNIVERSITY
技術說明:
透過分選精子晶片篩選,可將男性不孕症患者之精子活動力提升達80%以上,在40分鐘內。此晶片篩選出高質量比率精子的核心技術為逆流法。逆流法為精子在一適當之流體流速內,精子具有抵抗流體的現象,能逆流而上。
晶片流道透過特殊設計使流道成現漸擴流道,且流體具有適當的流速,能使具活力精子逆流在漸擴流道,而低活動力或死活之精子,因無法抵抗流體速度,而被沖至後端。
另外此晶片因透過適當的設計,無需連接額外幫浦來推動流體流動,只需將液體加入入料口,即會以適當的流速使精子具有逆流特性並進行篩選,增加操作方便性。分選後的高活動力精子,可應用於任何之後的不孕症之療程,例如IUI、ICSI、IVF。

By utilizing the intrinsic characteristic of upstream swimming of sperm to against an appropriate fluid velocity, the present sperm sorting microfluidic chip could increase sperm motility of infertile males up to 80% in just 40 minutes.
The microchannel of our chips is specially designed to be divergent to ensure appropriate fluid velocity for the high motile sperm to swim upstream into the divergent channels, whereas the low motile and nonviable sperm would be just washed away into wasted chamber.
Because of our special design, the appropriate fluid velocity for separating high motile sperm could be sustained by just loading fluid to the inlet chamber without the necessity of additional powered device. Thus, it is more convenient to operate on.
The present sperm sorting microfluidic chip could yield high motile sperm for subsequent infertility treatments in IUI, IVF or ICSI.
發明人:
曾繁根 特聘教授
潘力誠 教授
吳仁貴 博士
曾詠欽 研究生
王綏盛 研究生
連絡資訊:
賴淑真 03-5715131